LAUSR

BACKGROUND: Early childhood caries (ECC) is a problem in the field of dental health that occurs in infants and toddlers around the world. AIM: This study aims to relationship between CD14 and IgA levels with the ECC event children age 3–5 years. MATERIALS AND METHODS: This type of research is an observational cross-sectional comparative design between children with caries and non-caries. Samples are children aged 3–5 years with a history of consuming bottle milk. The number of samples was 28 people for each group (caries and non-caries) so that the total sample was 56 people. The CD14 and IgA levels measured using the ELISA method. The statistical test used is an independent t-test. p < 0.05 was said to be statistically significant. RESULTS: The results showed that the mean of CD14 levels was higher in the group caries than in the non-caries, while IgA levels were higher in the group non-caries than in the caries group. CONCLUSION: This study concluded that early caries childhood caries event children age 3–5 years increased the levels of IgA and decreased CD14 levels.