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This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural… Click to show full abstract
This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.
Keywords:
thymidine phosphorylase;
advances thymidine;
medicinal applications;
inhibitors syntheses;
recent advances;
phosphorylase inhibitors
Journal Title: Turkish Journal of Chemistry
Year Published: 2017
Link to full text (if available)
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Journal Title: Turkish Journal of Chemistry
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!