Photo by gabrielle_photo from unsplash
Regioand stereoselective synthesis of N -substituted azole acrylonitriles has been achieved smoothly in N,N -dimethylformamide (DMF) in the presence of potassium carbonate (K2 CO3) as a base catalyst. N -Substituted… Click to show full abstract
Regioand stereoselective synthesis of N -substituted azole acrylonitriles has been achieved smoothly in N,N -dimethylformamide (DMF) in the presence of potassium carbonate (K2 CO3) as a base catalyst. N -Substituted azole acrylonitriles were obtained in moderate to good yields (39%–87%) with a one-pot reaction between readily available N -acetylazoles and Baylis-Hillman nitriles. The structural determinations were accomplished by NOESY 1 H NMR and X-ray crystallography.
Keywords:
acylazole mediated;
synthesis;
stereoselective regioselective;
mediated stereoselective;
substituted azole;
azole acrylonitriles
Journal Title: TURKISH JOURNAL OF CHEMISTRY
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: TURKISH JOURNAL OF CHEMISTRY
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!