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Laboratory tests are useful in diagnosing rheumatic diseases, but clinicians should be aware of the limitations of these tests. This article uses case vignettes to provide practical and evidence-based guidance… Click to show full abstract
Laboratory tests are useful in diagnosing rheumatic diseases, but clinicians should be aware of the limitations of these tests. This article uses case vignettes to provide practical and evidence-based guidance on requesting and interpreting selected tests, including rheumatoid factor, anticitrullinated peptide antibody, antinuclear antibody, antiphospholipid antibodies, antineutrophil cytoplasmic antibody, and human leukocyte antigen-B27. Negative results are not always reassuring, and false-positive results pose risks.
Journal Title: Cleveland Clinic Journal of Medicine
Year Published: 2019
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