LAUSR

https://e-kcj.org Pulmonary hypertension (PH) is a group of diseases characterized by high pressure in the pulmonary arteries, leading to remodeling of the right ventricle. The most common initial symptoms of PH are exertional dyspnea and fatigue. Symptoms related to right heart disease, such as peripheral edema, abdominal pain with hepatic congestion, exertional syncope, or chest pain, may also appear. If left untreated, right ventricular failure progresses and can lead to death. Currently, a mean pulmonary arterial pressure of more than 20 mmHg measured by right heart catheterization at rest is defined as PH.1) This is different from the prior threshold of 25 mmHg or greater in acknowledgment of patients with a mean pulmonary artery pressure of 21 mmHg to 24mmHg have a higher risk of hospitalization and mortality compared to 20 mmHg or lower.2) Pulmonary arterial hypertension (PAH) is a 1 of the 5 groups of clinical classifications of PH. Mean pulmonary artery pressure greater than 20 mmHg, pulmonary artery wedge pressure of 15 mmHg or less, and pulmonary vascular resistance of at least 3 Wood units are the criteria for PAH (Group 1 PH).1) Despite the advances in the management of PAH, delayed diagnosis and the idea of untreatable PAH have made it difficult to treat this condition efficiently, and individuals with PAH continue to have a poor prognosis.