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Importance of etiology-based workup and diagnosis in acute multiple infarcts in multiple cerebral circulations

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Acute multiple infarcts in multiple cerebral circulations (AMIMCC) [anterior circulation: anterior cerebral artery, middle cerebral artery (MCA), and their major branches; posterior circulation: posterior cerebral artery and its major branches]… Click to show full abstract

Acute multiple infarcts in multiple cerebral circulations (AMIMCC) [anterior circulation: anterior cerebral artery, middle cerebral artery (MCA), and their major branches; posterior circulation: posterior cerebral artery and its major branches] are defined as noncontiguous infarcts involving more than one cerebral circulation (different territories). With the availability of advanced neuroimaging techniques, more and more of such types of cases are being diagnosed with ease. Etiology, pathomechanisms, clinical features, and prognosis of acute multiple infarcts (AMI) reflect wide variations in terms of geographical distribution (regions of the East versus West), location of infarcts, and age pattern of patients. Although, among various causes [Figure 1], cardioembolic etiology is predominantly encountered, other nonembolic causes are often overlooked, necessitating the cautious use of anticoagulation therapy for secondary prevention of such cases.[1]

Keywords: acute multiple; infarcts multiple; etiology; multiple infarcts; cerebral circulations; multiple cerebral

Journal Title: Neurology India
Year Published: 2019

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