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Cerebral Phaeohyphomycosis: Subacute Meningoencephalitic Presentation in a Child

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Cerebral phaeohyphomycosis is a rare but serious fungal infection of the central nervous system caused by dematiaceous septate fungi characterized by the presence of melanin-like pigment within the cell wall… Click to show full abstract

Cerebral phaeohyphomycosis is a rare but serious fungal infection of the central nervous system caused by dematiaceous septate fungi characterized by the presence of melanin-like pigment within the cell wall that is a pale brown to black. It is associated with poor prognosis despite aggressive treatment. We report a previously well 3-year boy with cerebral phaeohyphomycosis who had subacute meningoencephalitic presentation with refractory raised intracranial pressure and had fatal outcomes. The diagnosis was confirmed by histopathological examination of brain tissue obtained by brain biopsy.

Keywords: phaeohyphomycosis subacute; subacute meningoencephalitic; meningoencephalitic presentation; cerebral phaeohyphomycosis; phaeohyphomycosis

Journal Title: Neurology India
Year Published: 2021

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