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Makes reference to several cell type specific/selective AAV vectors have been reported and mentions endothelial cells and astrocytes. Makes no reference to other cells oligodendrocytes or microglia which have also… Click to show full abstract
Makes reference to several cell type specific/selective AAV vectors have been reported and mentions endothelial cells and astrocytes. Makes no reference to other cells oligodendrocytes or microglia which have also been successfully targeted with AAV using specific promoters or serotypes. Also, other targeted evolution attempts have been made to create cell specificity (as an example Juttner, J et al. (2019). Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans. Nat. Neurosci. 22, 1345-1356. doi: 10.1038/s41593-019-0431-2 ) why are these not referenced?
Journal Title: Neural Regeneration Research
Year Published: 2022
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