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Delayed activation of leg somatotopic fibers of an injured corticospinal tract in a patient with cerebral infarction

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Stroke is a leading cause of major adult disabilities, and motor weakness is one of the most serious disability-related sequelae of stroke. Most of the motor recovery in stroke patients… Click to show full abstract

Stroke is a leading cause of major adult disabilities, and motor weakness is one of the most serious disability-related sequelae of stroke. Most of the motor recovery in stroke patients is reported to occur within 6 months after stroke onset, and this period is deemed critical for motor recovery in stroke (Grefkes and Fink, 2020; Olafson et al., 2021). Therefore, active rehabilitation within 6 months after stroke onset is strongly recommended for hemiparetic stroke patients (Grefkes and Fink, 2020; Olafson et al., 2021). Research on delayed motor recovery after the critical period is important in stroke rehabilitation because it could provide a basis for rehabilitation strategies for chronic patients who failed to show good recovery during the critical period, even though they had a potential for good motor recovery. However, little is known about delayed motor recovery occurring more than 6 months after stroke onset (Jang et al., 2019).

Keywords: months stroke; motor; motor recovery; stroke onset; recovery

Journal Title: Neural Regeneration Research
Year Published: 2022

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