Brain synapses play a key role in neuronal communication: this “conversation” is at the basis of all brain activities and synaptic dysfunction leads to brain disorders. We study the modulators… Click to show full abstract
Brain synapses play a key role in neuronal communication: this “conversation” is at the basis of all brain activities and synaptic dysfunction leads to brain disorders. We study the modulators of this crucial synaptic function and we here present the evidence supporting the c-Jun N-terminal kinase (JNK) pathway as a pivotal actor in this scenario. The term “synapse” is derived from the Greek σύν (“together”) and ἅπτειν (“tap”, “connect”) meaning “conjunction”. Synapses are highly specialized cellular connections that represent the basic structural units of neuronal communication.
               
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