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Marchiafava‐Bignami disease (MBD) is a rare disorder of unknown etiology. Alcoholism is the greatest risk factor for MBD. The disease is characterized by progressive symmetrical demyelination and necrosis of corpus… Click to show full abstract
Marchiafava‐Bignami disease (MBD) is a rare disorder of unknown etiology. Alcoholism is the greatest risk factor for MBD. The disease is characterized by progressive symmetrical demyelination and necrosis of corpus callosum. The clinical features of MBD are non‐specific and it presents with a plethora of neuropsychiatric symptoms.[1] The modern diagnosis is almost always based entirely on the magnetic resonance imaging (MRI). There are several indications that this disease may be underdiagnosed. Early diagnosis and treatment of the disease leads to a favorable outcome.[2] We report a case of MBD in a middle‐aged man with chronic alcohol abuse who presented with a cluster of neuropsychiatric symptoms.
Journal Title: Annals of Indian Academy of Neurology
Year Published: 2022
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