LAUSR

Annals of Indian Academy of Neurology ¦ Volume 24 ¦ Issue 4 ¦ July-August 2021 624 Dear Editor, Bickers taff bra ins tem encephal i t i s (BBE) is an immune-mediated, rare form of encephalitis traditionally characterized by progressive, relatively symmetrical external ophthalmoplegia, ataxia, and disturbance of consciousness. Positive anti-GQ1b antibodies are found in 66% and abnormal brain MRI in 30% of patients. We herein report our patient who unusually had external plus internal ophthalmoplegia, hyperreflexia (not altered consciousness), normal brain imaging, and negative GQ1b profile. He was still diagnosed “Possible BBE” in accordance with postulated criteria for central nervous system involvement. We, therefore, with this report, emphasize on the clear-cut diagnostic criteria defining this disorder and also on its differentials based on acute bilateral ophthalmoplegia.