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Forward-viewing EUS-guided combined coil and glue injection in bleeding gastric varices secondary to splenic vein thrombosis in chronic pancreatitis

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Splenic vein thrombosis (SVT) is an important vascular complication of both acute and chronic pancreatitis, with 17%–55% of patients with SVT developing gastric varices (GVs).[1] Although bleeding from GV in… Click to show full abstract

Splenic vein thrombosis (SVT) is an important vascular complication of both acute and chronic pancreatitis, with 17%–55% of patients with SVT developing gastric varices (GVs).[1] Although bleeding from GV in SVT and pancreatitis is rare, it can be fatal. Endoscopic as well as EUS-guided N-butyl-2-cyanoacrylate glue injection has been shown to be a safe and effective treatment for bleeding GV in patients with portal hypertension due to cirrhosis.[2] However, unlike GV in cirrhosis, experience of endoscopic glue injection in bleeding GV due to SVT and pancreatitis is limited, and the results are not so encouraging with high re-bleeding rates.[3,4] Moreover, EUS-guided combined coil and glue injection in bleeding GV due to pancreatitis-induced SVT has not been previously studied. We retrospectively evaluated the safety and efficacy of EUS-guided combined coil and glue injection in bleeding GV in six patients (all males; mean age: 36.1 ± 6.7 years) with bleeding GV due to chronic pancreatitis (CP)-induced SVT.

Keywords: eus guided; glue injection; injection bleeding; pancreatitis

Journal Title: Endoscopic Ultrasound
Year Published: 2022

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