Traditionally, the decision to transfuse RBCs often rested on insensitive markers of oxygen delivery and consumption like the haemoglobin (Hb) level or the haematocrit. But the physiological responses that are… Click to show full abstract
Traditionally, the decision to transfuse RBCs often rested on insensitive markers of oxygen delivery and consumption like the haemoglobin (Hb) level or the haematocrit. But the physiological responses that are normally activated when the Hb concentration drops below a critical limit may be blunted in critical illness.[2] The hazardous nature of RBC transfusions, involving both infectious and non-infectious complications, is also well known. Therefore, it is evident that multiple factors should be considered when making the decision to transfuse RBCs in critically ill patients.
               
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