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Effect of intraoperative intravenous lignocaine infusion on the haemodynamic stability and postoperative recovery following intracranial aneurysm surgery: A case series

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Subarachnoid haemorrhage (SAH) presents as a neurosurgical emergency with symptoms ranging from headache to overt neurological deficit and cardiovascular instability. Intracranial aneurysmal rupture accounts for 85% SAH cases with a… Click to show full abstract

Subarachnoid haemorrhage (SAH) presents as a neurosurgical emergency with symptoms ranging from headache to overt neurological deficit and cardiovascular instability. Intracranial aneurysmal rupture accounts for 85% SAH cases with a subsequent significant morbidity (>50%) and mortality (>25%).[1,2] Surgery constitutes the definitive treatment. Herein, an optimal anaesthetic management revolves around the pivotal aim of maintenance of the perioperative haemodynamic stability and the adequacy of cerebral perfusion.[3] In this context, an intravenous lignocaine infusion is promising as it blunts the surgical stress response with an analgesic contribution.[4,5] Nevertheless, the dearth of evidence on its role in perioperative SAH setting prompted this index case‐series aimed at evaluating the effect of lignocaine infusion on the haemodynamic perturbations and recovery in 10 patients following aneurysm clipping surgery.

Keywords: surgery; intravenous lignocaine; lignocaine infusion; case series; haemodynamic stability

Journal Title: Indian Journal of Anaesthesia
Year Published: 2020

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