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A Report of Multiple Autoimmune Syndrome: Pemphigus Vulgaris Associated with Several Immune-Related Diseases after Thymectomy

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Sir, The co‐occurrence of three or more autoimmune disorders in an individual is called multiple autoimmune syndrome (MAS).[1] According to the combination of diseases, it is divided into three types.[2]… Click to show full abstract

Sir, The co‐occurrence of three or more autoimmune disorders in an individual is called multiple autoimmune syndrome (MAS).[1] According to the combination of diseases, it is divided into three types.[2] Currently, its pathogenesis is still unclear, and environmental factors and genetic factors are related to the occurrence of this disease.[3,4] Patients with a single autoimmune disease have a 25% risk of developing other autoimmune diseases.[5] The coexistence of several diseases in an individual is rare. Here, we report a patient with thymoma who suffered from myasthenia gravis, vitiligo, pure red cell aplasia, systemic lupus erythematosus, lichen planus, alopecia areata, and pemphigus vulgaris after thymectomy. This is a novel combination of MAS. The presence of thymoma should alert the physician to the possible presence of MAS.

Keywords: pemphigus vulgaris; autoimmune syndrome; multiple autoimmune; report multiple

Journal Title: Indian Journal of Dermatology
Year Published: 2020

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