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Sir, Dowling–Degos disease (DDD) is a rare autosomal dominant, progressive, reticulate pigmentary disorder. It usually appears after puberty.It is clinically characterized by hyperpigmented macules, papules and comedone‐like lesions on flexures… Click to show full abstract
Sir, Dowling–Degos disease (DDD) is a rare autosomal dominant, progressive, reticulate pigmentary disorder. It usually appears after puberty.It is clinically characterized by hyperpigmented macules, papules and comedone‐like lesions on flexures and perioral pitted scars.1,2 The pathogenesis of DDD has not been fully elucidated. However, loss of functional mutations in the keratin 5 gene has been described. Follicular pathology has also been attributed to its genesis.3
Keywords:
generalized dowling;
degos disease;
disease hypopigmented;
hypopigmented lesions;
dowling degos
Journal Title: Indian Journal of Dermatology, Venereology and Leprology
Year Published: 2018
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Journal Title: Indian Journal of Dermatology, Venereology and Leprology
Year Published: 2018
Link to full text (if available)
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recommendations!