© 2018 Indian Journal of Medical and Paediatric Oncology | Published by Wolters Kluwer Medknow Sir, Phyllodes tumor, a biphasic fibroepithelial tumor of the breast, arises de novo or rarely… Click to show full abstract
© 2018 Indian Journal of Medical and Paediatric Oncology | Published by Wolters Kluwer Medknow Sir, Phyllodes tumor, a biphasic fibroepithelial tumor of the breast, arises de novo or rarely from a preexisting fibroadenoma. Progression in phyllodes tumor is due to the crosstalk between epithelium and stroma, through signaling pathways and upregulation of certain genes.[1] Metaplasia of the stromal component is commonly seen but of the epithelial component is rare. We report a case of phyllodes tumor with borderline features, arising from a complex fibroadenoma and coexistent metaplastic changes in the duct epithelium with keratin cyst formation.
               
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