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Borderline phyllodes tumor arising in a complex fibroadenoma with extensive squamous metaplasia: A complex pathological presentation

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© 2018 Indian Journal of Medical and Paediatric Oncology | Published by Wolters Kluwer Medknow Sir, Phyllodes tumor, a biphasic fibroepithelial tumor of the breast, arises de novo or rarely… Click to show full abstract

© 2018 Indian Journal of Medical and Paediatric Oncology | Published by Wolters Kluwer Medknow Sir, Phyllodes tumor, a biphasic fibroepithelial tumor of the breast, arises de novo or rarely from a preexisting fibroadenoma. Progression in phyllodes tumor is due to the crosstalk between epithelium and stroma, through signaling pathways and upregulation of certain genes.[1] Metaplasia of the stromal component is commonly seen but of the epithelial component is rare. We report a case of phyllodes tumor with borderline features, arising from a complex fibroadenoma and coexistent metaplastic changes in the duct epithelium with keratin cyst formation.

Keywords: complex fibroadenoma; borderline; oncology; phyllodes tumor; arising complex

Journal Title: Indian Journal of Medical and Paediatric Oncology
Year Published: 2018

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