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Digital Gangrene in a Dialysis Patient Due to Calciphylaxis and Systemic Polyarteritis Nodosa: A Diagnostic Dilemma

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© 2018 Indian Journal of Nephrology | Published by Wolters Kluwer Medknow Sir, Calciphylaxis or calcific uremic arteriolopathy (CUA) is a potentially life‐threatening vasculopathy of the skin and subcutaneous tissues… Click to show full abstract

© 2018 Indian Journal of Nephrology | Published by Wolters Kluwer Medknow Sir, Calciphylaxis or calcific uremic arteriolopathy (CUA) is a potentially life‐threatening vasculopathy of the skin and subcutaneous tissues reported in association with chronic kidney disease (CKD). Risk factors include obesity, diabetes mellitus, female sex, white ethnicity, time on renal replacement therapy, and the use of coumarin anticoagulants.[1] CUA most frequently affects the lower limbs, mainly the buttocks and thighs. Digital necrosis due to CUA is very rare.[2] We describe an unusual case of polyarteritis nodosa (PAN) in a CKD patient with hyperparathyroidism and CUA presenting with digital gangrene.

Keywords: calciphylaxis; nephrology; digital gangrene; gangrene dialysis; polyarteritis nodosa

Journal Title: Indian Journal of Nephrology
Year Published: 2019

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