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Commentary: CRISPR gene editing for inherited retinal dystrophies: Towards clinical translation

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The clustered regularly interspaced short palindromic repeats (CRISPR) system won the Nobel Prize in 2020. What makes this technology intriguing is the ability of the CRISPR/ Cas9 effector molecules to… Click to show full abstract

The clustered regularly interspaced short palindromic repeats (CRISPR) system won the Nobel Prize in 2020. What makes this technology intriguing is the ability of the CRISPR/ Cas9 effector molecules to identify and bind to specific areas of the DNA, and make cuts or edits in those areas. While there were previous methods described to edit DNA (TALENs, Zinc Finger Nucleases), CRISPR has made the gene editing technology deliverable in terms of size and efficiency.

Keywords: editing inherited; commentary crispr; crispr; gene editing; crispr gene

Journal Title: Indian Journal of Ophthalmology
Year Published: 2022

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