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The current definition of IRIS includes five fundamental criteria: (1) confirmed case of HIV, (2) temporal association between the development of IRIS and initiation of highly active antiretroviral therapy (HAART),… Click to show full abstract
The current definition of IRIS includes five fundamental criteria: (1) confirmed case of HIV, (2) temporal association between the development of IRIS and initiation of highly active antiretroviral therapy (HAART), (3) specific host responses to HAART, such as a decrease in HIV-viral RNA load and an increase in CD4+ cell count (over 100 cells/mm3), (4) clinical deterioration characterized by an inflammatory process, and (5) exclusion of other causes that may lead to a similar clinical presentation.[2]
Journal Title: Indian Journal of Ophthalmology
Year Published: 2020
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