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Commentary: Congenital corneal anesthesia

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In conclusion, there appears to be a relationship between the functional loss (absent corneal sensation) and anatomical decrease (reduced subbasal nerve density) of corneal nerves in cases of CCA. Although… Click to show full abstract

In conclusion, there appears to be a relationship between the functional loss (absent corneal sensation) and anatomical decrease (reduced subbasal nerve density) of corneal nerves in cases of CCA. Although the sample size is small, considering the rarity of CCA, the findings of this study can be regarded as relevant. The poor ocular surface, anesthetised cornea, and self‐inflicted microtrauma are the leading causes of visual axis opacification in these high‐risk children. Visual acuity can be stabilized following the two‐third width tarsorrhaphy but is typically limited due to progressive corneal opacification, uncorrected refractive error, and amblyopia. Efficient ocular surface protection is crucial in eyes with CCA to retain long‐term functional vision. The assessment of ocular surface and corneal sensation might be confounded in a scarred cornea. Therefore, surrogate measures like corneal nerve density assessment, wherever applicable, must be imaged carefully.

Keywords: corneal; ocular surface; congenital corneal; commentary congenital; corneal anesthesia

Journal Title: Indian Journal of Ophthalmology
Year Published: 2021

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