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Commentary: Evidence of dengue virus in eviscerated specimens of panophthalmitis secondary to dengue fever: A possible cause-effect phenomenon

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The authors [XX}[7] have done commendable work in isolating dengue virus NS1 RNA in their eviscerated samples. However, the mere presence of the virus may not indicate a causative role… Click to show full abstract

The authors [XX}[7] have done commendable work in isolating dengue virus NS1 RNA in their eviscerated samples. However, the mere presence of the virus may not indicate a causative role in the panophthalmitis as the authors have rightly concluded. Further investigations are required to determine whether active viral replication or viral remnants or superadded bacterial infection account for this result. At presentation, a platelet count of 60,000 per microliter of blood was mentioned for the second case. Additional information about the platelet counts during dengue hemorrhagic fever and also during ocular presentation for all the cases can add additional insight into the disease course. The article could also mention whether single‐donor platelets or pooled platelets were administered to their first two cases.

Keywords: commentary evidence; dengue; fever; panophthalmitis; dengue virus; virus

Journal Title: Indian Journal of Ophthalmology
Year Published: 2022

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