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Received: 14‐Nov‐2021 Revision: 30‐Jan‐2022 Accepted: 14‐Mar‐2022 Published: 30‐Jun‐2022 Cite this article as: Khurana D, Balasubramaniyan MS, Hastak S, Chandrasekharan A. Dermolipoma in a case of split hand/foot malformation: A report of a novel ophthalmic presentation in a rare disease. Indian J Ophthalmol 2022;70:2613-5. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‐NonCommercial‐ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‐commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.