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Commentary: Impact of intraocular surgeries on corneal endothelial cells in patients with diabetes mellitus

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Corneal endothelial cells are indispensable for maintaining corneal transparency. Endothelial cell dysfunction may place the cornea at a greater risk of developing endothelium decompensation and consequent bullous keratopathy. Endothelial cells… Click to show full abstract

Corneal endothelial cells are indispensable for maintaining corneal transparency. Endothelial cell dysfunction may place the cornea at a greater risk of developing endothelium decompensation and consequent bullous keratopathy. Endothelial cells are known to show a decline in both qualitative and quantitative features, especially with increasing age owing to amitotic characteristics. Thus, endothelial cell damage can be significant in elderly individuals postoperatively. Consequent to any damage to the endothelial cell layer, the remaining contiguous cells enlarge and reposition to restore the functional anatomy. This is reflected as an increase in the cell size and a decrease in the percentage of hexagonal cells.[1]

Keywords: impact intraocular; endothelial cells; corneal endothelial; endothelial cell; commentary impact

Journal Title: Indian Journal of Ophthalmology
Year Published: 2022

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