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Pemphigus vulgaris (PV) is a rare severe autoimmune disease that is characterized by painful blisters and erosions on the skin and mucous membranes.[1,2] It is characterized by the loss of… Click to show full abstract
Pemphigus vulgaris (PV) is a rare severe autoimmune disease that is characterized by painful blisters and erosions on the skin and mucous membranes.[1,2] It is characterized by the loss of keratinocytes adhesion caused by circulating autoantibodies, mainly circulating IgG antibodies against desmoglein 3 or both desmoglein 1 and 3, the intercellular adhesion molecules. Generally, patients of PV present with oral lesions, which may precede cutaneous lesions by several months.[1] Ocular manifestations in PV are rare, the commonest reported being conjunctivitis.[3,4]
Journal Title: Indian Journal of Ophthalmology
Year Published: 2022
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