LAUSR

Ocular coloboma is a congenital defect caused by incomplete closure of the embryonic fissure during embryonic development. It can cause defects in the iris, crystalline lens, zonules, ciliary body, retina, choroid, and/or optic disc.[1] Nakamura et al.[2] reported isolated anterior segment, isolated posterior segment and involvement of both in around 36%, 39% and 24% cases respectively. The incidence of choroidal coloboma in the general population has been estimated to be around 0.14%.[3] It can be associated with retinal detachment (RD) in 2.4%–47.5% of eyes.[1] Uhumwangho et al.[4] showed that the chances of RD increased by a factor of 1.147 per year of the patient’s age. Histological studies have shown that the neurosensory retina is replaced by a rudimentary structure called intercalary membrane (ICM), while retinal pigment epithelium, Bruch’s membrane, choriocapillaris and choroid are absent.[1]