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Received: 13-Mar-2019 Revision: 20-Aug-2019 Accepted: 12-Sep-2019 Published: 14-Feb-2020 Cite this article as: Annapurna NV, Bagga B, Garg P, Joseph J, Sharma S, Kalra P, et al. Management of severe Acanthamoeba keratitis and complicated cataract following laser in situ keratomileusis. Indian J Ophthalmol 2020;68:515-6. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‐NonCommercial‐ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‐commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.