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Commentary: Clinical and biometric characteristics of pediatric eyes with nanophthalmos

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The development of the eye starts as early as three weeks of gestational age.[1] It involves the differentiation of specific cells from neuroepithelium and mesenchyme into various ocular tissues, which… Click to show full abstract

The development of the eye starts as early as three weeks of gestational age.[1] It involves the differentiation of specific cells from neuroepithelium and mesenchyme into various ocular tissues, which perform particular functions aiding in vision. Mutations in specific genes encoding for the development of the eye, such as PAX6, MRFP, TMEM98, BEST1, lead to developmental abnormalities in the eye.[2] These abnormalities can be as minimal as an isolated iris coloboma to gross defects like microphthalmos.

Keywords: biometric characteristics; clinical biometric; characteristics pediatric; pediatric eyes; eyes nanophthalmos; commentary clinical

Journal Title: Indian Journal of Ophthalmology
Year Published: 2022

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