LAUSR

However, in the index case, the presence of a duodenal neuroendocrine tumor points to the l iver mass to be a metastatic focus. The histomorphology of the metastatic site had a signet ring morphology in complete contrast to the morphology of the primary tumor. The absence of mucin, as demonstrated by lack of staining by PAS‐Alcian blue and immunoprofile of the tumor cells, helped in establishing the diagnosis.[4] MANEC and collision tumors (CT) are close differential diagnoses in this case. MANECs are characterized by a dual composition of neuroendocrine and adenocarcinoma, each contributing to at least 30% of the tumor.[5] While CT are juxtaposed tumors with two or more types of differentiation.[5] However, the