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Lepromatous leprosy-negative images giving the diagnostic clue

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On aspiration, the nodule yielded pus‐like material. Giemsa‐stained FNA smears revealed inflammatory exudate consisting of macrophages, few lymphocytes, and neutrophils. Macrophage showed foamy cytoplasm with intracellular unstained clefts interpreted as… Click to show full abstract

On aspiration, the nodule yielded pus‐like material. Giemsa‐stained FNA smears revealed inflammatory exudate consisting of macrophages, few lymphocytes, and neutrophils. Macrophage showed foamy cytoplasm with intracellular unstained clefts interpreted as negative images. Similar extracellular‐negative images were also seen [Figure 1]. The smears were then destained and restained with Fite stain which showed alcohol fast M. leprae in globi and singly [Figure 2]. Based on negative images and M. leprae in globi on Fite stain, cytological diagnosis of lepromatous leprosy was rendered. The case was then referred to dermatology OPD, and the diagnosis of lepromatous leprosy was confirmed on biopsy. Access this article online Website: www.ijpmonline.org PMID: 29323094 DOI: 10.4103/IJPM.IJPM_363_16 Quick Response Code: Im a g e

Keywords: giving diagnostic; negative images; lepromatous leprosy; images giving; leprosy negative; diagnostic clue

Journal Title: Indian Journal of Pathology and Microbiology
Year Published: 2017

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