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A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature

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Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after… Click to show full abstract

Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after the initiation of CBZ. We establish the probability of drug-induced liver injury using Council for International Organizations of Medical Sciences/Roussel Uclaf Causality Assessment Method causality assessment scale, and the patient had high probability with a score of 9. We briefly review the literature in this field discussing the scope of the problem, etiopathogenesis, clinical manifestation, course, and management.

Keywords: carbamazepine; case; review literature; report; cholestatic hepatitis; severe cholestatic

Journal Title: Indian Journal of Psychological Medicine
Year Published: 2017

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