LAUSR

whereas rechallenge with clonidine led to re-emergence of somnambulism. The patient was not prescribed any other medication and had no history of sleep disorder. Since somnambulism is a relatively common childhood parasomnia, the observed phenomenon could have been a separate entity (or related to ADHD or as an effect of sedation) unrelated to use of clonidine. However, the emergence and resolution of somnambulism with initiation and discontinuation of clonidine, respectively, may indicate an association. This case report is unique as it suggests an association between somnambulism and clonidine use. Clinicians will benefit from being mindful of this common yet bothersome adverse effect related to clonidine. Further clinical and translational studies are required to substantiate the underlying mechanism.