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Nucleosides take an important place in medicinal chemistry as the structural basis for the development of therapeutic agents. The chemistry of substituted base-modified nucleosides has been an interesting field of… Click to show full abstract
Nucleosides take an important place in medicinal chemistry as the structural basis for the development of therapeutic agents. The chemistry of substituted base-modified nucleosides has been an interesting field of study over the last two decades owing to their biological properties. This mini-review summarizes recent efforts on the synthesis of C5- and C8-alkynyl base-modified pyranonucleoside analogues using Sonogashira cross-coupling reaction under microwave irradiation.
Keywords:
rapid microwave;
chemistry;
microwave assisted;
assisted synthesis;
synthesis modified;
synthesis
Journal Title: Medicinal Chemistry
Year Published: 2017
Link to full text (if available)
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Journal Title: Medicinal Chemistry
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!