Ophthalmic drug delivery system is one of the most important routes of drug administration, but it is regarded as a challenging attempt encountered by pharmaceutical scientists.1 Most ophthalmic diseases are… Click to show full abstract
Ophthalmic drug delivery system is one of the most important routes of drug administration, but it is regarded as a challenging attempt encountered by pharmaceutical scientists.1 Most ophthalmic diseases are treated by topical eye drop instillation; however, several problems, such as poor bioavailability, are associated with these formulations.2 The drug is removed from the precorneal area within several minutes after instillation due to lacrimal secretion and nasolacrimal drainage.3,4
               
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