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Lemborexant: An adjuvant in difficult-to-control diabetes?

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Diabetes is a multi-faceted syndrome on which the brain is an etiopathogenetic factor, as well as a target organ for damage. Drugs which act on the brain, such as bromocriptine… Click to show full abstract

Diabetes is a multi-faceted syndrome on which the brain is an etiopathogenetic factor, as well as a target organ for damage. Drugs which act on the brain, such as bromocriptine and antipsychotic drugs, are known to influence glycaemic control. This article describes lemborexant, a dual oxexin receptor antagonist (DORA), and hypothesizes that it may be used as an adjuvant in difficult-to-control diabetes. Its utility should be explored in persons with insomnia and high fasting glucose, unregulated appetite, and diabetes distress.

Keywords: adjuvant difficult; control; control diabetes; lemborexant adjuvant; difficult control

Journal Title: JPMA. The Journal of the Pakistan Medical Association
Year Published: 2022

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