LAUSR

Nevus sebaceous(NS) is a congenital hamartoma of cutaneous structures including both surface epithelial and adnexal components. NS is usually removed by surgical excision. Here, we report an interesting case of NS on the face which showed good response to carbon dioxide (CO2) laser treatment combined with isotretinoin. A 22 - year - old female patient visited our dermatology clinic with skin lesion on the right cheek. Physical examination revealed multiple grouped, rice sized yellowish papules on the right cheek. Histopathologic findings revealed minimal papillomatosis, and acanthosis of epidermis with abundant of sebaceous gland proliferation in dermis. Based on these findings, we diagnosed her as NS. She was treated with CO2 laser for nevus ablation instead of surgical excision, because of location and size of the lesion with possibility of scar on face. After CO2 laser treatment, she took isotretinoin to prevent recurrence of NS. After 12 months later, lesion was well maintained without recurrence. Most investigators suggest that surgical excision is the treatment of choice of NS. However, remove nevus sebaceous by surgical excision leave linear scar. To minimize scar, there were several other treatment options include CO2 laser treatment.However, there was possibility of recurrence after laser treatment. To prevent recurrence, we treated her with isotretinoin and kept in good state for 12 months.