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Evaluation of 3T proton MR spectroscopy in the spinal cord – preliminary results

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Purpose 1H-magnetic resonance spectroscopy (1H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination.… Click to show full abstract

Purpose 1H-magnetic resonance spectroscopy (1H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination. The main goal of this study was to develop a routine protocol for MRS of intramedullary lesions. Material and methods A 1H-MRS protocol was set on a group of healthy volunteers. Forty-eight spectra were acquired in total. Thirty of them were acquired in cervical spinal cord, and the remaining 18 spectra were acquired in the thoracic spinal cord. Results In 1H-MRS of the spinal cord one of the most important problems is small voxel size. Mean voxel size in this study was 7 × 9 × 29 mm, which is much smaller than in brain examinations. Finally, almost 60% of spectra were of acceptable quality in volunteer examinations, which enabled the subsequent examinations. Conclusions Challenges of spinal cord spectroscopy were discussed, and the ability of providing additional diagnostic information was proven.

Keywords: spectroscopy; evaluation proton; spinal cord; spectroscopy spinal; proton spectroscopy

Journal Title: Polish Journal of Radiology
Year Published: 2022

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