LAUSR

AIM In this study, we aimed to retrospectively evaluate the relationships between morphometric measurements in craniovertebral junction and the possible genetic basis of the disease in Chiari type 1 patients undergoing surgical treatment. MATERIAL AND METHODS Morphometric and volumetric measurements of the posterior fossa from cranial and cervical radiological imagings of patients were performed. Cellar volüme, atlanto-dental distance, basal angle, clivus thickness, clivus lenght, distance between basion and dens, foramen magnum lateral distance, foramen magnum antero-posterior distance, cerebellar hemispher height, tentorial angle, dens height, foramen magnum plane were measured with 3D computerized tomography. RESULTS In patients with chiari type 1; basal angle was greater (125.29 ° ± 9.522 ° Vs. 112.33 ° ± 9.09 °) (p = 0.000), basion-dens distance was shorter (3.51 mm ± 1.695mm Vs. 5.27 ± 1.695mm) (p = 0.000), cerebellar hemispher height was longer (58.47 ± 5.143 mm Vs. 52.05 ± 5,008 mm) (p = 0.000), tentorium angle was greater (97.95 ° ± 11.321 ° vs. 87.79 ° ± 9.891 °) (p = 0.034) dens height was longer (13.9 ± 2.46 mm vs. 14.79 ± 1.631mm) (p = 0.041), cellar volume was smaller (41.4mm3 Vs. 53.3 mm3) (p = 0.034),and foramen magnum plane was larger (64.6 ° vs. 31.1 °) (p = 0.000) than control group. CONCLUSION It is concluded that many parameters including BA, FMP, BDD, CHH, TA, DH, and cellar volüme are abnormal, suggesting the need for focussing to the hormonal metabolism - related synchondral changes.