Heart failure (HF) is one of the most frequent causes of morbidity and mortality, affecting worldwide almost 1-2% of the adult population.1 In developed countries, it usually represents the final… Click to show full abstract
Heart failure (HF) is one of the most frequent causes of morbidity and mortality, affecting worldwide almost 1-2% of the adult population.1 In developed countries, it usually represents the final stage of coronary artery disease or untreated arterial hypertension, and its prognosis remains poor as well as the patient’s quality of life. Increasing evidence suggests congenital heart diseases (CHD) as one of the arising causes of HF.1 Indeed, the improvement of surgical techniques results in an increasing number of patients who reach the adult age and who develop heart failure.1 For these reasons, research in this field is very active and there is an urgent need to develop new preventive strategies that would prevent or early treat HF, rather than deal with it in its final stage.
               
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