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Article history: Received July 27, 2019 Received in revised format August 25, 2019 Accepted September 28 2019 Available online September 28 2019 The article was conducted on 529 textile enterprises in the Vietnam Textile and Garment Business Directory 2018 with the aim of assessing the impact of global supply chain management practices on competitive advantage and operational efficiency. After using PLS SEM analysis techniques on Smart PLS 3.0, the results show that the global supply chain management practices of Vietnam's textile and garment industry had a positive impact on the performance of Vietnam textile and garment enterprises. In addition, competitive advantages such as Customer Loyalty, Employee Satisfaction and Corporate Reputation had no intermediary role in the relationship between global supply chain management and operational efficiency in Vietnamese textile enterprises. . Growing Science, Canada by the authors; license 20 20 ©