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Blood Culture and Troponin Testing in Suspected Bacteraemic Admissions - Example of Risk Stratification Based on Clinical Testing.

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AIM To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing. METHODS We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood… Click to show full abstract

AIM To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing. METHODS We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression. RESULTS There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic. CONCLUSION Blood culture and hscTnT requests and results predict worse outcomes.

Keywords: blood; blood culture; troponin testing; culture troponin

Journal Title: Acute medicine
Year Published: 2022

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