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Combination treatment of allergic rhinitis using ketotifen fumarate and budesonide administered as nasal sprays
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OBJECTIVE This study aims to evaluate the clinical efficacy of ketotifen fumarate and budesonide administered as nasal sprays to treat allergic rhinitis. MATERIALS AND METHODS A total of 96 allergic… Click to show full abstract

OBJECTIVE This study aims to evaluate the clinical efficacy of ketotifen fumarate and budesonide administered as nasal sprays to treat allergic rhinitis. MATERIALS AND METHODS A total of 96 allergic rhinitis patients, who were admitted to our hospital in recent years, were selected as research subjectes. All patients were treated with ketotifen fumarate and budesonide administered as nasal sprays. Clinical efficacy was evaluated after treatment. RESULTS After treatment, the symptoms of nasal obstruction, nasal itching, sneezing, and runny nose significantly improved, and the score of these symptoms was significantly lower when compared to that before treatment (p < 0.05). After treatment, the eosinophils and IgE in peripheral blood of patients obviously reduced (p < 0.05). CONCLUSION Combination treatment of allergic rhinitis using ketotifen fumarate and budesonide administered as nasal sprays has a good clinical effect in treating allergic rhinitis, which is of great significance to improve the clinical symptoms and immune function of patients. Ketotifen fumarate and budesonide have good therapeutic effects on allergic rhinitis. The combination of these two drugs can rapidly relieve allergic symptoms.
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Keywords: ketotifen fumarate; treatment; allergic rhinitis; fumarate budesonide

Journal Title: International journal of clinical pharmacology and therapeutics
Year Published: 2020

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