LAUSR

The coronavirus disease 2019 (COVID-19) pandemic is a global health emergency with more than 200 million cases and 4.5 million deaths. Vaccination is one of the main preventive measures to bring the current COVID-19 pandemic under control. Vaccines may cause adverse events; however, the majority of those adverse events are not allergic. Anaphylaxis induced by vaccines occurs approximately at a rate of 1.3:1,000,000 doses of vaccine [1]. Recent data indicate that the incidence of COVID-19 vaccine-induced anaphylaxis is higher than that of all previous vaccines. The rates of anaphylaxis caused by the novel mRNA vaccine BNT162b2 (Pfizer-BioNTech, Mainz, Germany) and mRNA-1273 (Moderna, Cambridge, MA) are 4.7:1,000,000 doses and 2.8:1,000,000 doses, respectively [2]. Early data estimates the anaphylaxis rate after AZD1222 vaccination is 7.4:1,000,000 doses [3].