Production of antigens and antibodies in plant provide a potential approach for the development of vaccines for oral delivery.1 Traditional vaccines are facing challenges like storage, distribution and administration but… Click to show full abstract
Production of antigens and antibodies in plant provide a potential approach for the development of vaccines for oral delivery.1 Traditional vaccines are facing challenges like storage, distribution and administration but recently their safety and effectiveness has also raise many issues.2 Expression and secretion of recombination proteins, antigens and antibodies through transgenic hairy roots in confined media under controlled environment have opened door to simple, feasible and economic option compared to animal and bacterial systems.3,4 Hairy roots are non-photosynthetic and rapidly grow in simple culture media without requirement of phytohormones. Easy genetic manipulation, low-cost downstream purification and easy scaleup in bioreactors attract researchers to hairy roots.5
               
Click one of the above tabs to view related content.