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Computational Evaluation of ADMET Properties and Bioactive Score of Compounds from Encephalartos ferox

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Infectious diseases continue to devastate the developing world by presenting high mortality and morbidity rates annually.1 Medicinal plants are the predominant sources of natural lead compounds used in drug discoveries… Click to show full abstract

Infectious diseases continue to devastate the developing world by presenting high mortality and morbidity rates annually.1 Medicinal plants are the predominant sources of natural lead compounds used in drug discoveries and developments to combat the prevalence of infectious diseases.2 Their high potency and pharmacotherapeutic effects are owed to their diverse bioactive compounds. Among these compounds are alkaloids, saponins, tannins, glycosides and flavonoids.3 Thus, approximately 80% of the population in developing countries still rely on phytopharmaceuticals to prevent and treat different emerging and re-emerging infections.4

Keywords: score compounds; computational evaluation; admet properties; evaluation admet; bioactive score; properties bioactive

Journal Title: Polymer Journal
Year Published: 2020

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