LAUSR

Plants are an significant source of natural antioxidants that counter oxidative stress induced by an increase in free radicals / ROS such as superoxide O2− anion, hydroxyl radical HO− and peroxide as well1. The phytoconstituents research of these bioactive compounds in a plant is therefore of paramount importance, resulting to further biological and pharmacological studies. This study can be presented to develop herbal medicines that require the isolation of bioactive compounds from medicinal plants2. In recent research advances around the world the properties of medicinal plants have been studied because of no side effects, safety in contrast to the synthetics that are unsafe to human and environment. As a result people are more favourable to use natural compounds obtained from plants. It is great interest for scientists to focus on the search of biologically active compounds from plants as a natural source of useful drugs against infectious diseases3. Biological studies of herbal products (active ingredient) may be due to a variety of chemical components including flavonoids, phenolics, glycosides, anthocyanins, tannins, etc.4. Natural products are considered a drug source for several years, and have been chosen to interact with biological studies as a target5. The bioactive constituents in plant Phenolic compounds (PCs) for example, flavonoids are greater antioxidant activity6. Several studies have shown that many plants are rich source of antioxidants. One of these plants is S. grantii (Ephorbiaceae) that a plant species which belongs to a small genus of about 15 species. Plants from this genus for example (S. umbellatum, S. glaucescens, S.compactum, S.claycinum ) have different biological activities as anti-ulcer activity7, antiasthmatic effect8, antitumoral and anti-angiogenic effects9, antinoceptive anti-inflammatory, anti-plasmodial activity10. The aim of this work is to study the antioxidant activity of the isolated pure compounds from MeOH-H2O extract (70:30) of S. grantii for the first time.