LAUSR

Twenty-five spleens of adult, healthy dromedary of the local breed from the region of El Oued, Algeria, were collected at the slaughterhouse in order to carry out research to determine the macroscopic and microscopic structure of spleen in this specie, macroscopic study revealed that the spleen has a rectangular shape with a triangular section, rounded edges, a little bit striated, its surface is smooth in which the aspect of the capsule and the parietal surface is shiny and smooth, the morphometric study was carried out after classifying the sampled spleen in five groups according according to the animal's body weight which increases with age. Our study revealed that the groups show a different value of mass which declines towards a drop of the index, also the indexes of length and width are following a decreasing order. The histological study revealed that the zone occupied by stroma did not exceed 26.81 % of the total components of the capsule which is composed essentially of connective tissue and an inner layer of smooth muscle cells. Vascular and avascular trabeculae extend from the capsule. The immunohistochemistry study made it possible to visualize T lymphocytes of the splenic parenchyma using monoclonal antibodies where a statistical study was carried out to determine the composition of the various compartments of this organ. The localization of immunocompetent cells in the splenic parenchyma has been elucidated with antibodies specific for T lymphocytes. The red pulp occupied a maximum area of the spleen with an average of 68.1% composed of sinusoids venous, the cords extend between the sinuses and the interlobular zone contain many cells: macrophages, plasma cells, red blood cells, white blood cells and platelets.