A 53-year-old woman who has never smoked was admitted to the Department of Allergology and Pneumonology, University Hospital in Gdansk, Poland in order to modify current therapy of asthma. Since… Click to show full abstract
A 53-year-old woman who has never smoked was admitted to the Department of Allergology and Pneumonology, University Hospital in Gdansk, Poland in order to modify current therapy of asthma. Since the age of 18 years the patient had been treated for year-round allergic asthma. Medical history included poorly controlled steroid-dependent asthma (10 mg prednisone, orally) for more than 20 years. Therapy was complicated by steroid-induced osteoporosis and multiple rib fractures (Figs. 1, 2). Furthermore, due to vertebral osteoporosis the patient was treated nine times with cementoplasty. In 2013, after the first cementoplasty, significant deterioration of general health status, increased dyspnoea, and limited exercise tolerance occurred. The patient was diagnosed with chronic respiratory failure and since 2014 has remained on home oxygen therapy. During the stay at the department HRCT of the thorax was performed. Computed tomography (CT) scanning revealed linear shadow of high attenuation extending from the pulmonary trunk (where it forms a noose) through the right pulmonary artery to its right upper branch (Fig. 3), which had a density of 465 HU (comparable to the density of the cement material of the spine). Additionally, a similar linear shadow was revealed in the vena azygos, connected with the cement material in the vertebrae, and some minor calcification of bone density in the lung parenchyma. The differentiation included the remains of the intravascular catheter; however, angio-CT confirmed the presence of cementitious material in the pulmonary circulation and parenchyma (Figs. 4, 5). Although pulmonary complication of percutaneous vertebroplasty is rare, a few cases of thromboembolism and cement displacement into pulmonary circulation have been described so far.
               
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