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The entire study Dosimetric predictors of acute bone marrow toxicity in carcinoma cervix — experience from a tertiary cancer centre in India by Singareddy et al. [1] is based on… Click to show full abstract
The entire study Dosimetric predictors of acute bone marrow toxicity in carcinoma cervix — experience from a tertiary cancer centre in India by Singareddy et al. [1] is based on an assumption which rests on a shaky ground. The study assumes acute bone marrow toxicity is only due to pelvic radiation. Pelvic radiation portal covers the L5 vertebra, sacrum and central part of pelvic bones and at best covers 30% of bone marrow [2]. The remaining 70% of bone marrow compensates very well in an acute myelotoxicity period. Secondly, cisplatin which is used as concurrent chemotherapy, acts systemically on 100% of bone marrow causing acute myelosup-pression [3]. Cisplatin induced acute
Journal Title: Reports of Practical Oncology and Radiotherapy
Year Published: 2022
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